Aritcals & News

In bioreactor design, the selection of impellers is often treated as a "companion component"—simply pick any standard model that can rotate.

The safety and effectiveness of biological products depend on the precise implementation of downstream purification processes.

In the wave of biomanufacturing, pilot platforms are highly anticipated - they are the "bridge" connecting laboratory research and development with industrial production, and a key link in promoting the landing of innovative achievements.

As the core equipment in bioengineering, the manufacturing and operational details of bioreactors directly affect production efficiency and product quality.

In the biopharmaceutical industry, there exists an invisible yet crucial "red line" - bacterial endotoxin.

Recently, a colleague roasted: During an on-site inspection, the expert pointed out that the weld seam of a certain pipeline was located right below the support and hanger, and requested rectification. Many people were wondering, "How could the weld seam be in the wrong position? Isn't this too nitpicking?"

"40% of the fermentation broth was spilled" when the tank was being placed? Don't laugh, this can really happen

Beneath the halo of this GLP-1 "star drug", a larger strategy is quietly advancing - Eli Lilly is positioning gene therapy as the next core of growth.

Hyaluronic acid (HA), as a natural polysaccharide, is widely distributed in human skin, joint fluid, and connective tissue, and is a key component for maintaining skin moisture and elasticity.

When the cell culture system in a 200L pilot tank is scaled up "proportionally" to a 2000L pilot tank, phenomena such as yield fluctuations, metabolic disorders, and cell apoptosis are often not simply due to operational errors.

In the field of bioengineering, I often hear people say, "Our bacterial strains are particularly good, with high expression levels, but the results are not good after scaling up."

Based on efficient and stable biocatalysts, precise control of environmental parameters, directional guidance of metabolic flow, combined with real-time monitoring and feedback, while ensuring sterility, ultimately achieving efficient and stable synthesis of the target product.

AI and automation are driving the upgrade of this core capability

A few days ago, I had a meeting with a client who wrote the old saying again in the URS:
The internal cleaning of the fermentation tank must be 100% covered and there must be no dead corners

The safety and effectiveness of biological products depend on the precise implementation of downstream purification processes.

Fermentation of traditional Chinese medicine is not a new thing, its history can be traced back to ancient times. In the past, people often fermented traditional Chinese medicinal materials in pottery jars.

The Ministry of Industry and Information Technology has announced the shortlist for the "High Performance Bioreactor Innovation Task".

Today, we take stock of 5 cutting-edge papers in the field of synthetic biology by 2025.

Ergothionein (EGT) is a sulfur-containing amino acid produced by fungi and some bacteria, which the human body cannot synthesize on its own and relies entirely on dietary supplementation.

Peptide drugs "is one of the fastest-growing and most innovative sub sectors in the field of biomedicine in recent years.

Mass and heat transfer play a crucial role in the efficiency, product quality, and process stability of reactions and fermentation.

In the past year, research in the field of fermentation is no longer just about "adjusting parameters and adjusting production", but has begun to face the real pain points in industrial implementation: metabolic imbalance, product degradation, delayed detection, and extensive control

An authoritative review published in Chemical Engineering&Technology systematically outlines the core control strategies of fermentation processes, from basic open-loop to advanced intelligent control, providing a clear technical blueprint for industrial production.

Currently, bio based products account for 10% of petrochemical products worldwide, with an annual growth rate exceeding 20%.

This move marks a new stage of competition in the field of GLP-1 receptor agonists in China.

The answer to the question of whether second-hand bioreactors and fermentation tanks can be used is
It can be used, but the prerequisite is careful selection and thorough evaluation.

A few days ago, a friend who specializes in probiotic fermentation asked me:
Can the 300L fermentation tank from 2004 in the factory still be used? ”
I laughed - someone asked this question ten years ago.
And that 'antique' is still operating steadily in a university laboratory.

As the volume of the device increases, nonlinear changes occur in the physical field, transmission process, and cellular microenvironment.