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How to combine 9 types of fermented traditional Chinese medicine and 8 core microbial strains to achieve reduced toxicity, increased efficiency, and better absorption?

Sep 22,2025

biological fermentation


If you need to reduce toxicity (such as Aconitum and Pinellia ternata), prioritize choosing Aspergillus oryzae and yeast that can reduce toxic alkaloids/proteins.
If you need to increase efficiency (such as ginseng and astragalus), prioritize yeast and lactic acid bacteria that can convert saponins/polysaccharides.

If a compound needs to be processed, priority should be given to using mixed bacterial strains to achieve synergistic transformation of multiple components.

At present, research on fermented traditional Chinese medicine has shifted from "traditional experiential fermentation" (such as fermented black beans and Shenqu, using natural strains) to "precise and controllable fermentation" (using a single or clearly mixed strain).

Fermented traditional Chinese medicine is a type of Chinese medicine processing that utilizes the metabolic activity of microorganisms (bacteria, fungi, etc.) to transform the components in Chinese medicine raw materials

 (such as degrading toxic ingredients, generating new active substances, and increasing the dissolution rate of effective ingredients), thereby enhancing drug efficacy, reducing toxic side effects, or expanding indications.

1000l bioreactor price

1、 Common single fermented traditional Chinese medicine and core microbial strains
Single fermented traditional Chinese medicine is currently the most widely researched and applied type. It is recommended to choose Chinese medicine with clear efficacy and ingredients, and achieve "toxicity reduction and efficiency enhancement" through single or mixed strain fermentation.

2、 Common compound fermented traditional Chinese medicine and core microbial strains
Compound fermented traditional Chinese medicine is based on classic prescriptions or clinical experience prescriptions, and realizes "multi component collaborative transformation" through microbial fermentation

steel bioreactor

which is more consistent with the compatibility logic of "monarch, minister, assistant and envoy" of traditional Chinese medicine. It is commonly used in traditional Chinese patent medicines and simple preparations or health care products.

3、 The common characteristics and selection logic of core microbial 
strains In traditional Chinese medicine fermentation, the selection of strains is not random and must meet the principles of "safety, efficiency, and adaptability". Common core strains can be classified into three categories

continuous stirred tank fermenter

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