When traditional Chinese medicine encounters fermentation! Traditional wisdom+biological response=a hundred billion race track!
Medicine farmers push carts filled with medicinal herbs and shuttle through narrow streets, while buyers from all over the country carefully select high-quality Chinese medicinal herbs from their stalls.
This place, known as the "Capital of Chinese Medicine," has inherited a thousand year old culture of traditional Chinese medicine. Now, a revolution in traditional Chinese medicine is quietly happening here, bringing new vitality to ancient Chinese medicine. The protagonist of the story is the fermentation of traditional Chinese medicine.
1、 The Past and Present of Traditional Chinese Medicine Fermentation
Fermentation of traditional Chinese medicine is not a new thing, its history can be traced back to ancient times. In the past, people often fermented traditional Chinese medicine in pottery jars, which was simple but contained wisdom.
However, traditional fermentation has many drawbacks, such as difficulty in precise control of the fermentation process and unstable product quality.
The intervention of modern technology has brought about earth shaking changes in the fermentation of traditional Chinese medicine.
In a traditional Chinese medicine fermentation laboratory in Zhejiang, researchers are using advanced AI intelligent monitoring systems to fully control the fermentation process.
Temperature, humidity, microbial species and other parameters are displayed in real-time on the screen. Once an abnormality occurs, the system will immediately issue an alarm and automatically adjust.
This precise fermentation technology not only enhances the efficacy of traditional Chinese medicine, but also greatly improves the stability and safety of the product.
There are three main modes of traditional Chinese medicine fermentation technology today.
Solid state fermentation, in simple terms, refers to the cultivation of microorganisms in a solid-state environment using traditional Chinese medicine as the "culture medium".
It has low cost and simple process, but it is prone to batch instability during industrial production, just like using traditional handmade soy sauce. Although the taste is mellow, the taste of each batch may be different.
Liquid fermentation is quite different, as it involves mixing extracts of traditional Chinese medicine with a culture medium and conducting deep fermentation in a liquid environment.
It's like putting ingredients into a blender and thoroughly stirring before cooking, which can better release the effective ingredients in traditional Chinese medicine and greatly improve its bioavailability.
There is also a type of bidirectional fermentation, where microorganisms and traditional Chinese medicinal materials dance hand in hand, forming a symbiotic system of bacteria and medicine through interaction.
For example, the bidirectional fermentation of cicada like Penicillium and licorice residue can significantly increase the dissolution rate of glycyrrhizin, while also producing new active ingredients, just like how more treasures have been "transformed" into traditional Chinese medicine.

2、 The survival strategy of traditional Chinese medicine fermentation enterprises: fighting independently and collaborating with each other
In China, the fermentation industry of traditional Chinese medicine presents obvious regional distribution characteristics.
Enterprises from different regions, based on their own advantages, demonstrate their own strengths and cooperate with each other to promote the development of the industry.
Bozhou, located in the eastern region of Anhui Province, is a technological highland and industrial cluster for traditional Chinese medicine fermentation. The large pharmaceutical companies here have developed a series of high-quality traditional Chinese medicine fermentation products based on their strong financial strength and advanced technological equipment.
Fermented Ganoderma spore powder, through advanced ultrafine grinding technology and fermentation process, releases the active ingredients of Ganoderma spore powder more fully. The product has been warmly welcomed by the market since its launch.

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Jiaozuo, located in the central region of Henan Province, is renowned for its cultivation of traditional Chinese medicinal herbs.
The traditional Chinese medicine fermentation enterprises here fully utilize the advantages of local Chinese medicinal resources, adopt modern fermentation technology, and process traditional Chinese medicinal materials into high value-added fermented Chinese medicine products.
The fermented yam, a specialty of Jiaozuo, not only has a good taste, but also has the effect of invigorating the spleen and stomach, which is deeply loved by consumers.
Min County in western Gansu Province has abundant resources of Angelica sinensis. The traditional Chinese medicine fermentation enterprises in Minxian County focus on the fermentation research of Angelica sinensis. Through technical cooperation with the eastern region, they have developed products such as angelica fermentation essence liquid.
Large pharmaceutical companies occupy an important position in the market with their strong capabilities. They have met the demands of the high-end market through continuous technological innovation and product upgrades.

For example, a large pharmaceutical company has launched fermented traditional Chinese medicine decoction pieces, each of which undergoes strict fermentation processes and quality testing to ensure the high quality of the product, and is widely popular in professional channels such as hospitals and pharmacies.
Professional biotechnology companies focus on technological innovation as their core competitiveness and have established their own advantages in segmented fields. Having over 4000 patented strains, it's like a massive microbial 'treasure trove'.
Through precise fermentation technology, the most suitable strains of Chinese medicine can be selected for fermentation based on their characteristics, and a variety of Chinese medicine fermentation products with unique effects have been developed, providing technical solutions for many enterprises.
Innovative small and medium-sized enterprises are not to be outdone, as they seek opportunities in segmented markets through differentiation strategies. A small and medium-sized enterprise in Hangzhou has set its sights on young consumer groups and developed a series of functional skin care products such as traditional Chinese medicine fermentation facial mask.
These products combine the health benefits of traditional Chinese medicine with modern skincare concepts and are loved by young consumers.

3、 Future: Infinite possibilities for traditional Chinese medicine fermentation. The future of traditional Chinese medicine fermentation is full of infinite possibilities.
With the continuous advancement of technology and the continuous maturity of the market, the traditional Chinese medicine fermentation industry will usher in a broader development space.
In terms of technological development, precision fermentation technology will be more widely applied. Through cutting-edge technologies such as metagenomics, scientists can deeply analyze the interaction mechanism between traditional Chinese medicine and microorganisms, achieving precise compatibility of "one medicine, one bacterium".
Meanwhile, intelligent production will become the mainstream trend, utilizing AI to monitor fermentation parameters and combining blockchain technology to achieve full process traceability, which will greatly improve production efficiency and product quality.

In terms of personalized customization, with people's increasing attention to health, fermented traditional Chinese medicine products will be more tailored to individual needs.
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Based on the results of gut microbiota testing, tailoring traditional Chinese medicine fermentation plans for consumers will become a future development direction.
In the future, with continuous technological breakthroughs and market expansion, traditional Chinese medicine fermentation is expected to become a beautiful business card for traditional Chinese medicine to go global, continuing to write the modern legend of ancient Chinese medicine.
